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Changing the policy for intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy in Malawi

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dc.date.accessioned 2018-03-12T15:22:28Z
dc.date.available 2018-03-12T15:22:28Z
dc.date.issued 2017-05-15 en
dc.identifier.uri http://hdl.handle.net/20.500.11910/10924
dc.description.abstract The growing resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine (SP) treatment for uncomplicated malaria led to a recommendation by the World Health Organization for the use of artemisinin-based combination therapy. Inevitably, concerns were also raised surrounding the use of SP for intermittent prevention treatment of malaria during pregnancy (IPTp) amidst the lack of alternative drugs. Malawi was the first country to adopt intermittent prevention treatment with SP in 1993, and updated in 2013. This case study examines the policy updating process and the contribution of research and key stakeholders to this process. The findings support the development of a malaria research-to-policy framework in Malawi. Documents and evidence published from 1993 to 2012 were systematically reviewed in addition to key informant interviews. The online search identified 170 potential publications, of which eight from Malawi met the inclusion criteria. Two published studies from Malawi were instrumental in the WHO policy recommendation which in turn led to the updating of national policies. The updated policy indicates that more than two SP doses, as informed by research, overcome the challenges of the first policy of two SP doses only because of ineffectiveness by P. falciparum resistance and the global lack of replacement drugs to SP for IPTp. International WHO recommendations facilitated a smooth policy change driven by motivated local leadership with technical and financial support from development partners. Policy development and implementation should include key stakeholders and use local malaria research in a research-to-policy framework. en
dc.format.medium Print en
dc.subject MALARIA en
dc.subject MALAWI en
dc.subject POLICY IMPLEMENTATION en
dc.subject PREGNANCY en
dc.title Changing the policy for intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy in Malawi en
dc.type Journal Article en
dc.description.version Y en
dc.ProjectNumber N/A en
dc.Volume 16 en
dc.BudgetYear 2017/18 en
dc.ResearchGroup Population Health, Health Systems and Innovation en
dc.SourceTitle Malaria Journal en
dc.ArchiveNumber 9780 en
dc.PageNumber Online en
dc.outputnumber 8671 en
dc.bibliographictitle Mwendera, C.A., de Jager, C., Longwe, H., Phiri, K., Hongoro, C. & Mutero, C.M. (2017) Changing the policy for intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy in Malawi. <i>Malaria Journal</i>. 16:Online. en
dc.publicationyear 2017 en
dc.contributor.author1 Mwendera, C.A. en
dc.contributor.author2 de Jager, C. en
dc.contributor.author3 Longwe, H. en
dc.contributor.author4 Phiri, K. en
dc.contributor.author5 Hongoro, C. en
dc.contributor.author6 Mutero, C.M. en


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