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Perspectives of healthcare professionals of the neuropsychiatric side effects associated with efavirenz and its management

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dc.date.accessioned 2019-08-19T12:42:06Z
dc.date.available 2019-08-19T12:42:06Z
dc.date.issued 2019-02-12 en
dc.identifier.uri http://hdl.handle.net/20.500.11910/13361
dc.description.abstract Efavirenz is associated with neuropsychiatric side effects. The consequences of using efavirenz in human immunodeficiency virus (HIV)-positive patients with mental illness has not been conclusively established, the concern being that efavirenz may worsen the condition of an already mentally ill patient. The absence of guidelines and the lack of evidence for the use of efavirenz in this special population lead to uncertainty and, as a result, varying practices in the clinical setting. The aim is to determine the experiences of healthcare professionals caring for mentally ill people living with HIV (PLWH) who are using efavirenz, the associated neuropsychiatric side effects and the management thereof. A qualitative, descriptive, exploratory design was used to understand the phenomenon under study and to share the experiences of the participants. Semi-structured interviews were conducted. The data were analysed using thematic framework analysis and coded by the researcher as well as an independent coder. There were conflicting feelings concerning the use of efavirenz in PLWH with active mental illnesses. Some healthcare professionals were willing to prescribe and use efavirenz whilst others were not. All participants indicated that further elucidation in the guidelines on the possible side effects associated with efavirenz and suggested management strategies would be useful. The expansion of the South African National Guidelines for the Treatment of HIV should include descriptions of the side effects caused by antiretrovirals and management strategies thereof to empower healthcare professionals to make informed decisions regarding patient care for mentally ill PLWH. en
dc.format.medium Print en
dc.subject HIV/AIDS en
dc.subject MENTAL HEALTH en
dc.title Perspectives of healthcare professionals of the neuropsychiatric side effects associated with efavirenz and its management en
dc.type Journal Article en
dc.description.version Y en
dc.ProjectNumber N/A en
dc.Volume 23 en
dc.BudgetYear 2018/19 en
dc.ResearchGroup HIV/AIDS, STIs and TB en
dc.SourceTitle Health SA Gesondheid en
dc.ArchiveNumber 10707 en
dc.PageNumber Online en
dc.outputnumber 9722 en
dc.bibliographictitle Gaida, R., Truter, I. & Grobler, C. (2018) Perspectives of healthcare professionals of the neuropsychiatric side effects associated with efavirenz and its management . <i>Health SA Gesondheid</i>. 23:Online. en
dc.publicationyear 2018 en
dc.contributor.author1 Gaida, R. en
dc.contributor.author2 Truter, I. en
dc.contributor.author3 Grobler, C. en


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